European Journal of Biotechnology and Bioscience

European Journal of Biotechnology and Bioscience


European Journal of Biotechnology and Bioscience
European Journal of Biotechnology and Bioscience
Vol. 7, Issue 3 (2019)

In-vitro antibacterial activity of various extracts from Terminalia ivorensis A. Chev. (Combretaceae) stem bark against some Beta-Lactamase-producing bacteria strains


Ouattara Karamoko, Ouattara Abou, Kamagaté Tidiane, Touré Kahafénéchon Martial, Soro Pégnonsienrè Lacina, Bagré Issa

This study was undertaken to investigate the antibacterial properties of various extracts from the stem bark of T. ivorensis on three extended-spectrum β-lactamases-producing bacteria strains growth (Acinetobacter sp. IPMQ/C3GR, Escherichia coli KGTNE/RCFQ, and Klebsiella pneumoniae ATCC/1833). Antibacterial activity of hydro-alcoholic (EBeth), aqueous (Faq), and hexane (Fhex) extracts was assessed using agar disc-diffusion method and liquid medium micro dilution method. Aqueous fraction (Faq) and hydro-alcoholic (EBeth) extracts showed significant activity (p≤0.05) against all bacteria strains except hexane fraction (Fhex). Faq and EBeth exhibited the lowest Minimum Inhibition Concentration (12.50 mg/ml), while Minimum Bactericidal Concentration ranged between 12.50 to 25 mg/mL respectively. Therefore, Faq and EBeth extracts of T. ivorensis showed a bactericidal power against all bacterial strains tested.
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