Vol. 7, Issue 3 (2019)
In-vitro antibacterial activity of various extracts from Terminalia ivorensis A. Chev. (Combretaceae) stem bark against some Beta-Lactamase-producing bacteria strains
Author(s): Ouattara Karamoko, Ouattara Abou, Kamagaté Tidiane, Touré Kahafénéchon Martial, Soro Pégnonsienrè Lacina, Bagré Issa
Abstract: This study was undertaken to investigate the antibacterial properties of various extracts from the stem bark of T. ivorensis on three extended-spectrum β-lactamases-producing bacteria strains growth (Acinetobacter sp. IPMQ/C3GR, Escherichia coli KGTNE/RCFQ, and Klebsiella pneumoniae ATCC/1833). Antibacterial activity of hydro-alcoholic (EBeth), aqueous (Faq), and hexane (Fhex) extracts was assessed using agar disc-diffusion method and liquid medium micro dilution method. Aqueous fraction (Faq) and hydro-alcoholic (EBeth) extracts showed significant activity (p≤0.05) against all bacteria strains except hexane fraction (Fhex). Faq and EBeth exhibited the lowest Minimum Inhibition Concentration (12.50 mg/ml), while Minimum Bactericidal Concentration ranged between 12.50 to 25 mg/mL respectively. Therefore, Faq and EBeth extracts of T. ivorensis showed a bactericidal power against all bacterial strains tested.