Phytochemical and antimicrobial study of Alstonia scholaris (L) R. of family apocynaceae
Safeekun Nisha, AR Singh
The present deals phytochemical and antimicrobial study of Alstonia scholaris (L) R. of family Apocynaceae. revealed marked variation in overall content of phenolics in leaf, bark and latex extracts. The leaf extract had highest content of overall phenolics followed by bark and latex extracts. In the leaf extract, flavonoids and proanthocyanidins were present in abundance with values observed 89.34 mgQE/g DW and 92.32 mgCE/g DW, respectively, whereas the phenolics were only 49.67 mgGAE/gDW. In the bark extract, level of flavonoids and phenolics were comparatively lower than leaf extract, however proanthocynidins (66.82 mgCE/g DW) was found significantly higher. Latext extract had lowest content of phenolics (26.1 mgGAE/g DW), flavonoids (16.02 mgQE/g DW) and proanthocynidins (21.34mgCE/g DW). Methanol extracts of A. scholaris leaves, bark and latex extracts exhibited strong antioxidant activities in terms of scavenging DPPH free radicals. Antimicrobial microbial response have been observed.