European Journal of Biotechnology and Bioscience

European Journal of Biotechnology and Bioscience


European Journal of Biotechnology and Bioscience
European Journal of Biotechnology and Bioscience
Vol. 9, Issue 4 (2021)

Biochemical, resistance and epidemiological profile of Salmonella and Shigella gastroenteritis isolated in chad from 2010-2020


Bessimbaye Nadlaou, Mayoré Atéba Djibrine, Djimadoum Mbanga, Frank Edgard Zongo Ragomzingba, Choua Ouchemi, Nicolas Barro

Bacterial infections are varied and recurrent in Chad. This is why we undertook between 2010 and 2020 a study to identify Salmonella and Shigella in N’Djamena (Chad). Diarrheal stools were collected in sterile vials from patients with digestive disorders and cholera patients. Identification of Salmonella and Shigella was performed according to standard clinical microbiology methods. Significant differences were observed between the proportions of patients aged 0 to 5 years (29.43%) and 21 years and over (53.61%), between negative (72.16%) and positive (28%) with probabilities of 0.001 and 0.02 respectively. Of the 254 bacteria isolated, the prevalence of Shigella was 71.25% followed by Salmonella (29%) with an overall prevalence of 10.14%. La résistance observée chez des souches de Salmonella et Shigella s’est avérée être une multi résistance puisqu’elle s’exprimait à l’égard de plusieurs familles d’antibiotiques: un taux moyen l’ordre de 14,45% de résistance aux bêtalactamines, 41% Trimethoprim-Sulfamethoxazole, 16,53% chloramphénicol, 39% tétracycline et 39,31% gentamicine respectivement. Les antibiotiques les plus actifs étaient de la famille de: quinolones (nalidixic acid), fluoroquinolone (ciprofloxacin), Carbapénème (ertapeneme), avec des proportions de 96%, 98,42%, et 100% respectivement. This study has shown that Salmonella and Shigella pose a real public health problem in Chad. It also made it possible to identify the need to follow the antibiotic profile in order to establish effective antibiotic therapy and to set up a prevention program adapted to the health of the population.
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How to cite this article:
Bessimbaye Nadlaou, Mayoré Atéba Djibrine, Djimadoum Mbanga, Frank Edgard Zongo Ragomzingba, Choua Ouchemi, Nicolas Barro. Biochemical, resistance and epidemiological profile of Salmonella and Shigella gastroenteritis isolated in chad from 2010-2020 . European Journal of Biotechnology and Bioscience. 2021; 9(4): 1-10.