European Journal of Biotechnology and Bioscience

Authors
Prasenjit Mitra, Tanaya Ghosh, Prasanta Kumar Mitra

Abstract
Anti-peptic ulcer activity of TLC separated fractions of root extract ofAstilbe rivularis, a plant of Eastern Himalaya, was studied in experimental peptic ulcer models. Gastric ulcers were induced in rats by ethanol, HCl indomethacin, swimming stress and pyloric ligation while duodenal ulcers were developed in the animals by cysteamine. Results were compared with omeprazole, a known drug for peptic ulcer. It was found out that one TLC separated fraction of root extract of Astilbe rivularis exerted anti peptic ulcer activity against all the models studied. The anti-peptic ulcer activity of the fraction was, however, less than that of omeprazole.