In this study, the comparative analysis of some wild edible berries viz., Berberis lycium, Duchesnea indica, Rubus fruticosus, Viburnum grandiflorum and Ziziphus jujube were made for immunomodulatory, antioxidant and phytochemicals activities. Methanol extracts of Rubus fruticosus fruit, Berberis lycium leaves and Viburnum grandiflorum fruit demonstrated promising antioxidant potential as compared to Ziziphus jujube and Duchesnea indica. Immunomodulatory studies for these extracts were also determined by evaluating Humoral antibody (Hab) and Delayed type hypersensitivity response (DTH) in immune suppressed mice. It was found that methanol extracts of Rubus fruticosus fruit, Berberis lycium leaves, Viburnum grandiflorum fruit have considerable enhancing effect on Humoral antibody and DTH response as compared to Duchesnea indica leaves and Ziziphus jujube fruit. The results depicted that Rubus fruticosus, Berberis lycium, and Viburnum grandiflorum exhibited relatively better antioxidant and immunomodulatory potential than Ziziphus jujube and Duchesnea indica. Future experimentation on this species could explore their chemical compositions for better understanding of their biological activities.
Madhulika Bhagat, Vishawdeep Singh Jamwal, Preeti choudhary Anapurna Kaul, Jasvinder Singh. Immunomodulatory, Antioxidant potential and phytochemical study of some wild berries of North-Western Himalayan region: A Comparative study. European Journal of Biotechnology and Bioscience, Volume 3, Issue 12, 2015, Pages 50-56