European Journal of Biotechnology and Bioscience

In the presentrninvestigation, an attempt has been made to determine the acute toxicity ofrnsodium fluoride and its toxicological effects on hematological parameters ofrnfreshwater edible fish, Rita rita from Bhima river near Solapur. Fishesrnwere exposed to different groups like predetermined LC₀ (30mg/l), LC_10rn(35mg/l) and LC₅₀ (75mg/l) concentrations of sodium fluoridern(during December 2008 and January 2009). Alterations in hematologicalrnparameters were studied at the end of 24, 48, 72 and 96 hours of treatment. Thernfindings of this study showed that parameters like R.B.C, W.B.C, Hemoglobinrn(Hb), Hemocrite (HCT), Mean corpuscular hemocrite (MCH) and Mean corpuscularrnhemocrite concentration (MCHC) levels were decreased in the sodium fluoriderntreated fishes. The observed changes indicated that the hematologicalrnparameters can be used as bioindicator of sodium fluoride stress in freshwaterrnedible fish, Rita rita.