Nosocomial fungal infections and its control measures using medicinal plant of marine origin
Sambandam Thamizharasan, Natarajan Anbusaravanan
The aim of the study was to evaluate the antifungal activity of the extracts of medicinal marine algal plant Padina gymnosphora against Candida albicans, a nosocomial fungal strain. The plant was selected on the basis of the previous study report on ethnobotanical uses. Aqueous and methanol extracts of the plant was screened in vitro for their antifungal activity against the nosocomial fungus Candida albicans. 100μl concentrations of both extracts were used in well diffusion assay. The study showed the anti-candidial effect, both in methanol and aqueous extracts. The growth inhibition rate of Candida albicans was 12mm in aqueous extract. But the inhibitory zone of methanol extract was seen above 22mm. The standard antibiotics show the inhibition zone as 26mm.The methanol extracts of plant was more efficient as compared to the aqueous extract.
Sambandam Thamizharasan, Natarajan Anbusaravanan. Nosocomial fungal infections and its control measures using medicinal plant of marine origin. European Journal of Biotechnology and Bioscience, Volume 5, Issue 1, 2017, Pages 36-38