Nanotechnology based sustained action drug delivery system: A review
Praveen Kumar Gupta, Lingayya Hiremath, S Narendra Kumar, Ajeet Kumar Srivastava, Navyashri Shankarnarayan, Vidyashree S, Simran A Singh
In recent times, nanotechnology has gained significant importance in the drug delivery scenario. In fact, various forms of nanoparticles – organic and inorganic, dendrimer, Nano crystals are used for the purpose of drug delivery. Since drugs are entrapped into biodegradable nanostructures, nanomaterial’s act as Nano medicines and thereby releasing the drugs in a sustained manner at the specific target sites could be possible. Therefore now a days it’s possible to screen the drugs against chemical and enzymatic conditions. Also the drugs physicochemical properties can be protected. Hence, nanotechnologies and their uses in the drug delivery system have stated gaining attention. From the few decades in past, extensive research has been carried out using accurate drug release systems acting as carriers for undersized and bulky drug molecules in sustained action controlled delivery methods. Thus, uses of nanoparticles proven to be effective in modifying and improving the drug pharmacokinetic and pharmacodynamics properties. This paper describe the details of various polymers which are useful in the development of nanoparticles and to enhance the therapeutic benefits of delivered medicines by using nanoparticle based carriers.
Praveen Kumar Gupta, Lingayya Hiremath, S Narendra Kumar, Ajeet Kumar Srivastava, Navyashri Shankarnarayan, Vidyashree S, Simran A Singh. Nanotechnology based sustained action drug delivery system: A review. European Journal of Biotechnology and Bioscience, Volume 5, Issue 4, 2017, Pages 60-67