European Journal of Biotechnology and Bioscience

European Journal of Biotechnology and Bioscience


European Journal of Biotechnology and Bioscience
European Journal of Biotechnology and Bioscience
Vol. 6, Issue 6 (2018)

Antibacterial and acute toxicity studies of culinary leaves from Adansonia digitata L. (Malvaceae) and Amaranthus cruentus L. (Amaranthaceae) growing in Côte d’Ivoire


Touré Abdoulaye, Kablan Ahmont Landry Claude, Ahoua Angora Rémi Constant, Kabran Aka Faustin, Adiko N’dri Marcelline, Attioua Koffi Barthélémy

Adansonia digitata L. (Malvaceae) andAmaranthus cruentus L. (Amaranthaceae) leaves are consumed by people of northern of Côte d’Ivoire. Methanol extracts from these leaves have been investigated for their antibacterial activity and acute toxicity in rats. Antibacterial activity was evaluated by using agar diffusion and microdilution in 96 wells methods against Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa. The extracts acute toxicity were carried out based on OECD guidelines 423 with high limit dose of 2000 mg/kg body weight of test animal. All extracts had bacteriostatic activities against test bacteria with MICs values greater than 30 mg/ml. The highest dose administered did not produced mortality or changes in general behaviour of test animals. In conclusion consumption of leaves of Adansonia digitata and Amaranthus cruentus may prevent bacterial infections and is not toxic in experimental animals.
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How to cite this article:
Touré Abdoulaye, Kablan Ahmont Landry Claude, Ahoua Angora Rémi Constant, Kabran Aka Faustin, Adiko N’dri Marcelline, Attioua Koffi Barthélémy. Antibacterial and acute toxicity studies of culinary leaves from Adansonia digitata L. (Malvaceae) and Amaranthus cruentus L. (Amaranthaceae) growing in Côte d’Ivoire. European Journal of Biotechnology and Bioscience, Volume 6, Issue 6, 2018, Pages 24-29
European Journal of Biotechnology and Bioscience