Chemopreventive and therapeutic efficacy of astaxanthin against cancer: A comprehensive review
Keshamma E, Sridhar B T, Anil Kumar, Laxmi Kirana Pallathadka, Harikumar Pallathadka
Astaxanthin is a natural product with oxidant-quenching and anti-inflammatory properties. Inflammation plays a crucial function in the propagation and survival of cancer. It can reduce the spread of malignant cells and prevent the development of inflammatory mucosal ulcers and pockets. It has been selected as a novel metastasis inhibitor. Astaxanthin causes apoptosis in several in vitro studies, including both oral and liver cancer cells. In the early stages of these studies, very promising findings have been produced, with expectations that human application is likely validated. Cancer-fighting evidence shows the ability of astaxanthin to combat cancer. Cancer cells expand rapidly, penetrate, migrate, and attach to healthy tissues and organs. The study is required to understand the mechanisms of action further and identify novel targets for the molecule. The author would like to clarify that this is not an endorsement of astaxanthin's actions in cancer, but rather a recommendation that further research is needed to confirm the beneficial effects of this natural product on cancer treatment. It can be used as a novel therapeutic agent for chemotherapy-induced oral mucositis. It has been selected as a Novel metastasis inhibitor. AXT inhibits the EMT pathway in colon cancer cells and can reduce breast cancer cells' proliferation and growth. In mice with AD, we observed that AST could exacerbate dermatitis and pruritus. Astaxanthin can address human health problems, including cancer, cardiovascular, and neurodegenerative diseases. It is hoped that human application is likely to be validated for use in cancer treatment. Astaxanthin can address human health problems, including cancer, cardiovascular, and neurodegenerative diseases. It can be used as a novel therapeutic agent for chemotherapy‐induced oral mucositis.
Keshamma E, Sridhar B T, Anil Kumar, Laxmi Kirana Pallathadka, Harikumar Pallathadka. Chemopreventive and therapeutic efficacy of astaxanthin against cancer: A comprehensive review. European Journal of Biotechnology and Bioscience, Volume 9, Issue 4, 2021, Pages 30-38